Gatehouse
Working Group
 

This event is by invitation only.

Meeting Summary: Cell types are the building blocks of organismal complexity and diversity and are themselves the product of complex dynamical processes of development (differentiation) and evolution. A previous SFI working group has proposed a novel theory of cell type origination and evolution published in Nature Reviews Genetics in 2016 (NRG 17:744-757). This follow-up working group will now develop a more operationalized application of the previously developed theoretical model. This is especially pertinent as new data from single cell sequencing allow us to trace the trajectories of cell linages with ever increasing accuracy. However, this data deluge is in dire need for a theoretical foundation grounded in the developmental and evolutionary dimensions of cells as complex systems.

Purpose: 
Research Collaboration
SFI Host: 
Manfred Laubichler, Detlev Arendt, Günter Wagner

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