Tuesday, April 30, 2019
8:30 am - 9:00 am Day 1 Continental Breakfast (outside SFI Noyce Conference Room)
 
9:00 am - 9:15 am Welcome - Amy P Chen (SFI), David Krakauer (SFI)
 
9:15 am - 9:30 am Introductions and Workshop Overview - Jean Carlson (UCSB), Mercedes Pascual (Univ. Chicago)
 
9:30 am - 12:00 pm Session I: Immune System: Architecture and Dynamics - Mercedes Pascual (Univ. Chicago)
 
  1. Universal laws and architectures in complex networked systems with applications to aging and immune systems - John Doyle (Caltech) 
  2. Allometric Scalings and Immune Dynamics - Andrew P. Dobson (Princeton), Chris Kempes (SFI)
  3. Immunosenescence in Coupled Innate/Adaptive Immune Architecture - Jean Carlson (UCSB), Eric Jones (UCSB) 
  4. Specific and generalized immunity in rotavirus multi-strain dynamics - Pamela Martinez (Harvard) 
12:00 pm - 1:00 pm Day 1 Lunch (outside SFI Noyce Conference Room)
 
1:00 pm - 3:30 pm Session II: Immune System: Aging and Heterogeneity - Jean Carlson (UCSB)
 
  1. Influenza viruses encountered in childhood leave a lifelong imprint - Katie Gostic (UCLA) 
  2. Original antigenic sin and antigenic maps - Sarah Cobey (Univ. Chicago), Phil Arevalo (Univ. Chicago), Marcos Viera (Univ. Chicago)
  3. The arrow of time as seen through the immune system and the physiological internalization of time - Micaela Martinez (Columbia Univ.)
  4. Immune selection, extreme antigenic variation, and a novel epidemiological threshold - Mercedes Pascual (Univ. Chicago), Qixin He (Univ. Chicago) 
3:30 pm - 4:00 pm Day 1 PM Break
 
4:00 pm - 5:00 pm Day 1: Discussion, development of themes, and structure of breakout groups
 
Wednesday, May 1, 2019
8:30 am - 9:00 am Day 2 Continental Breakfast (outside SFI Noyce Conference Room)
 
9:00 am - 10:00 am Summary of Day 1: Each speaker from Day 1 gives a 5 minute, two slides summary (intended to bring late arrivals up to date)
 
10:00 am - 12:00 pm Session IV: Short Talks for Late Arrival - Jean Carlson (UCSB)
 
  1. Biozzi mice and the antibody-lifespan connection - Andrea L. Graham (Princeton)
  2. Understanding immunosenescence with an interplay of innate and adaptive immunity - Shenshen Wang (UCLA), Jiming Sheng (UCLA) 
  3. Drawing trajectories through disease space and visualizing how they vary - David Schneider (Stanford) 
12:00 pm - 1:00 pm Day 2 Lunch (outside SFI Noyce Conference Room)
 
1:00 pm - 3:00 pm Day 2 Working Group Breakout Session I
 
3:00 pm - 3:30 pm Day 2 PM Break
 
3:30 pm - 5:00 pm Day 2 Working Group Breakout Session II
 
6:00 pm Group Dinner at Radish & Rye
 
Thursday, May 2, 2019
8:30 am - 9:00 am Day 3 Continental Breakfast (outside SFI Noyce Conference Room)
 
9:00 am - 12:00 pm Session V: Aging and the Arrow of Time –Breakout Group Updates and Broader Themes of the SFI/JSMF Initiative

Discussion leaders selected from each breakout group

Working group topics may include:

1.    Interaction of the adaptive and innate immune system in the dynamics of infection

2.    the role of early-childhood exposure (‘imprinting’) in later immune protection and in defining the temporal changes of the antigenic map

3.    the allometric scaling of the immune system dynamics with organism size.                              

Broader topics may include:

1.    Complex Networks: Architecture, Robustness, and Fragility,

2.    Memory, Dynamics, and Timing,

3.    Scaling and Complex Time.

12:00 pm - 1:00 pm Day 3 Lunch (outside SFI Noyce Conference Room)
 
1:00 pm - 3:00 pm Day 3 Working Group Breakout Session I
 
3:00 pm - 3:30 pm Day 3 PM Break
 
3:30 pm - 5:00 pm Day 3 Working Group Breakout Session II
 
Friday, May 3, 2019
8:30 am - 9:00 am Day 4 Continental Breakfast (outside Collins Conference Room)
 
9:00 am - 9:30 am Discussion of plans for wrapping up and final session breakout group presentations
 
9:30 am - 11:30 am Day 4 Working Group Breakout Session I
 
11:30 am - 1:00 pm Day 4 Lunch (outside Collins Conference Room)
 
1:00 pm - 3:00 pm Day 4 Working Group Breakout Session II
 
3:00 pm - 3:30 pm Day 4 PM Break
 
3:30 pm - 5:00 pm Session VI: Breakout group presentations, discussion of themes, and next steps