Wang, Xutong; Zhangwei Du; Kaitlyn E. Johnson; Remy F. Pasco; Spencer J. Fox; Michael Lachmann; Jason S. McLellan and Lauren Ancel Meyers

During rollout of coronavirus disease vaccination, policymakers have faced critical trade-offs. Using a mathematical model of transmission, we found that timing of vaccination rollout would be expected to have a substantially greater effect on mortality rate than risk-based prioritization and uptake and that prioritizing first doses over second doses may be lifesaving.